The threat landscape
Pathogens are evolving and spreading - more variants, more antimicrobial resistance, and more emergence across borders and populations.
From complexity to clarity.
Achieving true clarity on pathogens requires genomic science — along with the systems and strategy to act on it. Theiagen brings expertise across all three.

Genomics can deliver high-resolution insights. Realizing that potential takes the right expertise, systems, and strategy.
Pathogens are evolving and spreading - more variants, more antimicrobial resistance, and more emergence across borders and populations.
Generating sequencing data is no longer the bottleneck. Building the right approach and program to turn that data into useful insights is.
Microbiology, bioinformatics, epidemiology, and computer science are each specialized disciplines. Assembling and operationalizing all four around a specific environment is rarely straightforward.
Our breadth of expertise comes from working across pathogen challenges with labs of every kind. We structure each engagement around our clients’ needs.
The full range of disciplines working together. Theiagen’s scientific depth spans microbiology, bioinformatics, epidemiology, and software systems - the complete range required to understand and operationalize pathogens at a genomic level.
Learn more about ScienceBuilt around what you already have. We build the workflows, pipelines, and technology infrastructure that turn genomic data into clear, defensible answers within your existing environment.
Learn more about SystemsEvery engagement is different. We listen first, then structure an approach around exactly what you need - nothing more, nothing less.
Learn more about StrategyDifferent organizations face different constraints, timelines, and reporting needs. Find out how we work with organizations like yours.
Supporting the public health bioinformatics infrastructure your community depends on.
02Pathogen genomics clarity - the capability your hospital clients will expect next.
03Pathogen genomics for definitive outbreak decision-making.
04Pathogen genomics at the scale and rigor federal biosurveillance requires.
05Genomic insights to investigate contamination and guide food and water safety decisions.
Theiagen is strongest at the handoff between complex genomic evidence and the people who have to act on it.
We collaborate across laboratories, technology platforms, and public-health networks to move genomic programs forward.





Theiagen shares what we’re learning from the lab, from the field, and from genomic outbreak intelligence work.
Commercial lab opportunity, hospital expectations, and the broader business case for pathogen genomics.
Learn more about White papersExamples include unclear infection investigations, Candida auris outbreak insight, and California COVIDNet surveillance scale.
Learn more about Case studiesPublic resources, publications, training, podcast episodes, technical briefs, and newsletters.
Visit resourcesClear answers to common questions about how Theiagen works, what we build, and who we support.
Pathogen genomics is the use of DNA and RNA sequencing to understand infectious organisms, including bacteria, viruses, fungi, and parasites. By analyzing genomic data, laboratories can identify outbreaks, track transmission, detect emerging variants, and support public health decision-making.
Pathogen genomics provides a level of detail that traditional laboratory methods cannot match. It helps organizations determine how pathogens are related, monitor antimicrobial resistance, identify transmission pathways, and improve outbreak response and public health bioinformatics programs.
Genomic sequencing reveals genetic relationships among pathogens that are not visible through conventional testing. This allows laboratories and public health agencies to identify outbreaks earlier, understand transmission dynamics, and make more informed decisions using standardized public health genomic pipelines.
Pathogen genomics is used by public health laboratories, federal agencies, commercial reference laboratories, hospital and health systems, food and water safety organizations, and academic and research institutions.
Theiagen combines microbiology, bioinformatics, epidemiology, and software systems to help organizations build sustainable pathogen genomics capabilities rather than isolated tools.
Theiagen specializes in pathogen genomics and pairs scientific depth with operational implementation, transparent workflows, training, and ongoing expert support.
Sequencing equipment alone does not create a successful pathogen genomics program. Effective programs require NGS pipeline automation, bioinformatics workflows, data interpretation, quality systems, and trained personnel who can translate genomic information into decisions and actions.
The phrase reflects Theiagen’s approach of helping organizations transform complex genomic data into clear, defensible, and actionable answers for surveillance, outbreak response, and public health decision-making.
NGS pipeline automation uses standardized, reproducible workflows to process raw sequencing data with minimal manual intervention. Automated pipelines reduce errors, improve throughput, and make genomic programs more scalable and sustainable.
Cloud-based genomic analysis uses scalable cloud computing infrastructure to process, store, and interpret genomic sequencing data. It supports collaboration, large-scale surveillance, and rapid scaling during outbreak response.
Genomic data security and compliance are built into engagements from the outset, including alignment with applicable regulatory frameworks, data governance, IP protection, and secure cloud or on-premises infrastructure configuration.
Yes. Theiagen’s workflows are built on open-source bioinformatics tools including Nextflow, WDL, and publicly available pipeline frameworks wherever appropriate, supporting transparency, reproducibility, interoperability, and practical reuse across public health and laboratory environments.
Unlike generalist bioinformatics consulting firms, Theiagen specializes in pathogen genomics and combines microbiology, bioinformatics, epidemiology, and software systems under one engagement.
Let’s start with a conversation.